Imaging Services
Preclinical Imaging Services
At Ekam Imaging, we offer a comprehensive range of preclinical MR imaging services for studies involving both awake and anesthetized animals.
Our broad range of capabilities includes:
Species
- Rat
- Mouse
- Vole
- Marmoset
MR imaging techniques
- Awake fMRI / PhMRI.
- Awake Resting State Functional connectivity.
- Diffusion weighted imaging /Diffusion tensor imaging.
- MR spectroscopy.
- T1/T2 mapping
- MR Contrast characterization.
- Alzheimer’s Disease (Rat) APOE- ε2/3/4
- Parkinson’s Disease (Rat) PINK 1
- Concussion /Traumatic brain injury / Mild head injury in rats.
- Type 2 Diabetes and SVD model.
- Multiple Sclerosis in rat and ferret
- Drugs of abuse in rat – opioids, cocaine, amphetamines, cannabis
- PTSD
- Aggression
- Neurodegeneration
Supporting Services:
- Consulting on the efficacy of the compound and the desired testing procedure
- Design of the study protocol and experiments
- Animal purchase (or growing of specific animal disease models) and housing
- Pre-imaging animal preparation: Surgery and/or dosing (if required)
- Acclimation of animals to equipment/setup
- Collection of blood tissue samples
- Data compilation and analysis
- Data interpretation
- Report generation.
Our Services
Awake Animal Imaging
While anesthetics are commonly used to reduce motion in MRI studies, they can have notable effects on the central nervous, cardiovascular, and respiratory systems.
Behavioral Assays
Assessing neurological traits and events in rodents is an essential part of neurological research, and behavioral testing plays a vital role in evaluating these factors.
MRI Brain Atlases
Ekam has developed its own MRI based 3D animal brain atlases, which segment the brain into distinct areas for use in registration, and data analysis.
Animal Models for Human Disorders
Animal models of human disorders are used in research to understand the biological mechanisms that underlie these disorders and to develop new treatments. While it is not always ……..
MRI Coils
Awake animal imaging has revolutionized preclinical research in neuroscience, allowing researchers to capture more accurate and clinically relevant data by eliminating the
Neurotoxicity
Approximately one quarter of small molecules in drug development intended for CNS indications fail in clinical trials due to neurotoxicity issues, which are often not identified during drug discovery stages.
Data Analysis and Interpretation
With Ekam's data analysis package, we offer quick and precise analysis of each subject. Our proprietary algorithms use registration and atlas-based segmentation to accurately identify brain regions.
Contact imagingservices@ekamimaging.com
for more details and Atlas purchase
